abstract：:The PLC/PRF/5 human hepatoma cell line producing hepatitis B surface antigen (HBsAg) was studied to determine whether infectious hepatitis B virus (HBV) was also being produced. 2 chimpanzees with no previous exposure to HBV and no serologic markers of past or active HBV infection were inoculated intravenously with 50...

journal_title：Intervirology

authors： Tabor E,Copeland JA,Mann GF,Howard CR,Skelly J,Snoy P,Zuckerman AJ,Gerety RJ

更新日期：1981-01-01 00:00:00

abstract：:The amino acid sequences of the virion proteins of 7 definitive tobamoviruses have been compared. The results show that the proteins may be arranged unequivocally in a single dendrogram which, by analogy with similar comparisons of other sets of homologous proteins, probably reflects their phylogeny. The magnitude of ...

journal_title：Intervirology

authors： Gibbs A

更新日期：1980-01-01 00:00:00

abstract：:The distribution of related sequences between the genomes of pseudorabies virus (PRV) and herpes simplex virus, types 1 (HSV-1) and 2 (HSV-2), was determined. Approximately 7% of the sequences in PRV are shared by HSV-1 and HSV-2 DNAs. By means of the Southern blot technique, it was found that the homologous sequences...

journal_title：Intervirology

authors： Rand TH,Ben-Porat T

更新日期：1980-01-01 00:00:00

abstract：:A BHK/21 cell line persistently infected by an arenavirus is described. During four consecutive passages, 30-45% of the cells showed granular cytoplasmic antigen by indirect immunofluorescence, employing both Argentine hemorrhagic fever convalescent sera and sera from animals immunized with Junin virus. Virus isolated...

journal_title：Intervirology

authors： Carballal G,Cossio PM,Rabinovich A,Oubiña J,Arana RM

更新日期：1980-01-01 00:00:00

abstract：:The Holland strain of anatid herpesvirus (AHV) was 2-to 10-fold more efficiently plaqued under liquid medium or semisolid medium containing methylcellulose than in media containing agar, agarose, or Nobel agar. Virus adsorption was complete in 45 min, with the maximum virus titers obtained under liquid medium at 48 h ...

journal_title：Intervirology

authors： Attanasio R,Olson R,Johnson JC

更新日期：1980-01-01 00:00:00

abstract：:Healthy common marmosets from two separate colonies, one in England and one in France, were found to have antibodies cross-reacting with Epstein-Barr virus structural antigens (EBV-VCA). All seropositive animals were at least 2 years old. Experimental EBV infection of marmosets of different ages led to seroconversion ...

journal_title：Intervirology

authors： de-Thé G,Dubouch P,Fontaine C,Wedderburn N,Carter RL,Edwards MB,Cohen B

更新日期：1980-01-01 00:00:00

abstract：:A seroepidemiological survey of the human syncytial (foamy) virus was done by means of an indirect immunofluorescence test on 1,717 sera from nine different Pacific island territories. The specificity of the reaction was verified by neutralization tests. The study indicated that the virus is ubiquitous in this part of...

journal_title：Intervirology

authors： Loh PC,Matsuura F,Mizumoto C

更新日期：1980-01-01 00:00:00

abstract：:Purified Junin virus was disrupted by nonionic detergent treatment (Triton X-100), and subviral components were separated by ultracentrifugation. Only the soluble fraction, containing all of the major glycoprotein (mol.wt. 38,000), induced the formation of neutralizing antibodies in laboratory animals and protected th...

journal_title：Intervirology

authors： Cresta B,Padula P,de Martinez Segovia M

更新日期：1980-01-01 00:00:00

abstract：:Cytomegalovirus-infected human fibroblasts developed large numbers of fine microvilli within 90 min after addition of virus. The structure of these microvilli gradually changed as the infection proceeded, although the infected cells were easily detected by their large number of processes. These processes may be involv...

journal_title：Intervirology

authors： Garnett HM

更新日期：1979-01-01 00:00:00

abstract：:Proteins released from herpes simplex virus type 1 (HSV-1)-and type 2 (HSV-2)-infected HEp-2 cells have been characterized by the crossed immunoelectrophoretic technique. Both HSV type-common and type-specific antigens were found in the tissue culture medium 24 h after infection. Antigen Ag-6, an HSV-1-specific antige...

journal_title：Intervirology

authors： Norrild B,Vestergaard BF

更新日期：1979-01-01 00:00:00

abstract：:The transcriptases of several influenza viruses were tested for pH and temperature dependence and for thermal stability. Marked differences in pH dependence and thermostability were determined. ...

journal_title：Intervirology

authors： Broucek J,Závadová H,Vonka V

更新日期：1979-01-01 00:00:00

abstract：:Analysis of translation products synthesized in vitro in the presence of a mixture of brome mosaic virus (BMV) RNAs 1, 2, 3, and 4 usually shows a predominance of coat protein, coded by RNA4. The proportion of products directed by RNAs 1 and 2 decreased at saturating concentrations of BMV RNA and in the presence of 7-...

journal_title：Intervirology

authors： Pyne JW,Hall TC

更新日期：1979-01-01 00:00:00

abstract：:An RNA virus was isolated from Trichoplusia ni larvae infected with inoculum of the baculovirus of Autographa californica. Physicochemical characterization has revealed a 35-nm virus with a density in CsCl of 1.3 g/cm3 and a sedimentation coefficient of 200S. The virus consisted of 10--15% single-stranded RNA with an ...

journal_title：Intervirology

authors： Morris TJ,Hess RT,Pinnock DE

更新日期：1979-01-01 00:00:00

abstract：:In chicken cells infected by Sindbis virus and exposed to a variety of membrane-active compounds, virus release was inhibited. In infected cells exposed to antiserum directed against the virion glycoproteins E1 or E2, retinol, cortisone, Pb++ or insulin, the processing of two Sindbis virus precursor polypeptides which...

journal_title：Intervirology

authors： Scupham RK,Sagik BP,Bose HR Jr

更新日期：1979-01-01 00:00:00

abstract：:When Vero cells infected with Junín virus are cultured in the presence of 16 mM glucosamine, no infectious virus is produced and no surface antigens or virions are detected. Cytoplasmic viral antigen, however, is synthesized normally. ...

journal_title：Intervirology

authors： Martínez Peralta LA,León ME,Coto CE,Laguens RP

更新日期：1979-01-01 00:00:00

abstract：:By 48 h postinfection, 40--80% of SV40-infected CV-1 cells have undergone irreversible injury as indicated by trypan blue staining. Nevertheless, at this time the lysosomes of these cells appear as discrete structures after vital staining with either acridine orange or neutral red. Lysosomes, vitally stained with neut...

journal_title：Intervirology

authors： Einck KH,Norkin LC

更新日期：1979-01-01 00:00:00

abstract：:In a synchronous infection of cowpea chlorotic mottle virus in cowpea leaves, the three largest viral RNA components were synthesized throughout the infection at relatively constant ratios of two molecules of component 3 to one each of components 1 and 2. Component 4 (the coat protein message) was produced minimally d...

journal_title：Intervirology

authors： Dawson WO

更新日期：1978-01-01 00:00:00

abstract：:The critical point dried (CPD) whole cell technique was applied to the study of the morphogenesis and morphology of rabies virus and vesicular stomatitis virus (VSV) in mouse neuroblastoma and baby hamster kidney (BHK) cells. With the stereoscopic technique, progeny viruses at the cell surface and within the cytoplasm...

journal_title：Intervirology

authors： Iwasaki Y

更新日期：1978-01-01 00:00:00

abstract：:The effect of caffeine on cytomegalovirus (CMV) replication in human embryo lung (HEL) and human embryo kidney (HEK) cells was studied. In HEL cultures, nonirradiated CMV yielded up to 6.7 times more plaques in caffeine-treated cultures than in control cultures. Virus growth curves exhibited different profiles, depend...

journal_title：Intervirology

authors： Yamanishi K,Fogel M,Rapp F

更新日期：1978-01-01 00:00:00

abstract：:SDS-polyacrylamide slab gel analysis of selected primate and nonprimate adenoviruses has shown these viruses to differ significantly at the polypeptide molecular level. It follows that data derived from study of a single adenovirus serotype are unique to that serotype and are not representative of the adenovirus group...

journal_title：Intervirology

authors： Marusyk RG,Cummings GT

更新日期：1978-01-01 00:00:00

abstract：:Cultures of human cells transformed by SV40 were found to release infectious virus, even after several passages in vitro. Virus shedding by these cultures did not depend on propagation of virus from cell to cell, as it was not affected by anti-SV40 antiserum that could effectively block virus propagation in acutely in...

journal_title：Intervirology

authors： Lomax CA,Thirion JP,Bourgaux-Ramoisy D

更新日期：1978-01-01 00:00:00

abstract：:Four tetraploid cell lines were derived from the Epstein-Barr virus (EBV)-carrying, nonproducer Burkitt lymphoma line Raji after colcemide treatment. EBV early antigen (EA) was induced by P3HR-1 virus superinfection and by iododeoxyuridine treatment. Inducibility was reduced in all tetraploid lines compared to the nea...

journal_title：Intervirology

authors： Shapiro IM,Andersson-Anvret M,Klein G

更新日期：1978-01-01 00:00:00

abstract：:Marek's disease herpesvirus (MDHV) isolated from chickens free of naturally occurring avian leukosis virus (ALV) infection produced characteristic foci in both chicken embryo fibroblast (CEF) and chicken kidney cell (CKC) cultures. MDHV-A, which was extracted from the feather follicle epithelium of chickens naturally ...

journal_title：Intervirology

authors： Campbell WF,Kufe DW,Peters WP,Spiegelman S,Frankel JW

更新日期：1978-01-01 00:00:00

abstract：:The use of glutaraldehyde (GA)-treated chicken red blood cells (RBC) for purification of Sendai virions by adsorption and elution was found to be advantageous over the use of untreated RBC. Biologic and enzymatic activities and structural components of the purified virions were compared with those of the original viri...

journal_title：Intervirology

authors： Hosaka Y,Hosokawa Y

更新日期：1977-01-01 00:00:00

abstract：:Plants mixedly infected with the U2 strain of tobacco mosaic virus (T2MV) and sunnhemp mosaic virus (SHMV) and grown at 35 degrees, yield particles of the same modal lengths (300 and 40 nm) as those found in plants singly infected with SHMV, but not in plants infected with T2MV, which yield only the long particles. At...

journal_title：Intervirology

authors： Skotnicki A,Gibbs A,Shaw DC

更新日期：1976-01-01 00:00:00

abstract：:Acute hemorrhagic conjunctivitis (AHC) virus strains isolated in eight different areas during epidemics of AHC were tested for the reproductive capacity at 33, 37 and 39 degrees. All of the 25 strains tested grew better at 33 degrees but restrictively at 39 degrees. The degree of temperature sensitivity varied slightl...

journal_title：Intervirology

authors： Miyamura K,Sasagawa A,Tajiri E,Kono R

更新日期：1976-01-01 00:00:00

abstract：:Solubilized envelope antigens (glycoproteins) of Sendai virus were purified in a DEAE-Bio-Gel A column. Monospecific antisera were prepared against the antigens, designated HN and F glycoproteins. These glycoproteins are antigenically distinct. Immunodiffusion analyses of the envelope antigens of three representative ...

journal_title：Intervirology

authors： Urata DM,Seto JT

更新日期：1975-01-01 00:00:00

abstract：:Serial passage of undiluted herpes simplex virus types 1 and 2 resulted in cyclic production of infectious and defective virions. Defective virus production was characterized by the appearance of a new species of viral DNA with a higher bouyant density in CsCl than standard viral DNA. Measurement of the infectivity ti...

journal_title：Intervirology

authors： Murray BK,Biswal N,Bookout JB,Lanford RE,Courtney RJ,Melnick JL

更新日期：1975-01-01 00:00:00

abstract：:Guanidine (GD) inhibited tobacco mosaic virus (TMV) RNA synthesis at two different steps, depending on the concentration of GD used. The time-course of inhibition by 40 mM GD coincided with the time-course of RNA synthesis. However, 10 mM GD inhibited an earlier step that occurred prior to viral RNA synthesis. ...

journal_title：Intervirology

authors： Dawson WO

更新日期：1975-01-01 00:00:00

abstract：:Biochemical studies on human coronavirus, strain 229E, indicate that the RNA is present in the virion in association with protein as a ribonucleoprotein (RNP) complex. Morphological studies have revealed that this nucleocapsid is probably a continuous helical RNP. ...

journal_title：Intervirology

authors： Kennedy DA,Johnson-Lussenburg CM

更新日期：1975-01-01 00:00:00

abstract：:6/94 virus, isolated originally from a multiple sclerosis (MS) patient, was compared antigenically with related parainfluenza type 1 strains. These included two Sendai strains of mouse and two Sendai strains of reported human origin as well as the HA2 strain. By standard hemagglutination inhibition (HI) or hemadsorpti...

journal_title：Intervirology

authors： Lief FS,Loh W,Meulen VT,Koprowski H

更新日期：1975-01-01 00:00:00

abstract：:A serologic comparison was performed by immune electron microscopy between hepatitis A antigen (related to the MS-1 strain of hepatitis A virus) and a viral isolate, CR69(076), from the stool of a patient in Costa Rica with viral hepatitis. CR69(076) was not antigenically related to hepatitis A antigen but was related...

journal_title：Intervirology

authors： Dienstag JL,Pelon W,Tyeryar F,Purcell RH

更新日期：1975-01-01 00:00:00

abstract：:Influenza PR8 particles resulting from strong treatment with caseinase C are spikeless, devoid of neuraminidase and hemagglutinin 1 and 2 glycopeptides, and contain a Schiff-negative polypeptide of about 13,000 molecular weight which exists as traces in intact virions. Their M-protein polypeptide content is reduced to...

journal_title：Intervirology

authors： Reginster M,Rentier B,Dierickx L

更新日期：1975-01-01 00:00:00

abstract：:The results of this study show that the synthesis of the inner mitochondrial membrane phospholipid, cardiolipin, is markedly inhibited following infection of human embryonic lung or hamster embryo fibroblast cells with herpes simplex virus type 1 or 2. The synthesis of other phospholipids, i.e., phosphatidylcholine, p...

journal_title：Intervirology

authors： Tucker T,Steiner MR,Steiner S

更新日期：1974-01-01 00:00:00